Zeta Plus™ Encapsulated System Scale-Up Filter Capsule, EXT, with ZB Series Media

• Two layers of complementary porosities provide high contaminant holding capacity, economical filtration and reliable particle reduction
• Highly charged resin provides negatively charged particle adsorption
• FDA Drug Master File and USP Class VI Biological Reactivity Tests eases validation and regulatory submissions
• Self-contained, single-use capsules are available in three convenient sizes for scale-up and benchtop studies
• Low hold-up volume for minimal fluid loss and novel shape to maintain the same lenticular flow path as larger capsules and cartridges
• Low hold-up volume for minimal fluid loss
• Novel shape to maintain the same lenticular flow path as larger capsules and cartridges

We developed the Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with ZB Series Media to provide economical small scale clarification of pharmaceutical, biological, bioprocess, and cosmetic fluids. Our depth filtration media is composed of inorganic filter aid, cellulose and a positively charged resin system that pulls negatively charged contaminants from the fluid.

Our Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with ZB Series Media are optimized for polishing clarification of mammalian cell harvest fluids and for protection of downstream sterilizing grade membrane filters. Their strong positive charge can provide more reduction of negatively charged contaminants than mechanical filtration alone. These products are manufactured to stringent quality controls that provide reproducible product performance from filter to filter, lot to lot. When used as a pre-filter, the high contaminant holding capacity of Zeta Plus Scale-Up Filter Capsules, EXT, with ZB Series Media can prolong the life of the final stage filter. Pharmaceutical Grade Media Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with ZB Series Media are manufactured to controls described in our Drug Master File on record with the FDA. Certificates of Quality are included with every filter. These filters meet the requirements of USP Class VI Biological Reactivity Tests and meet the strict requirements specified in the Drug Master File, including product control and traceability. Encapsulating High Performance When faced with the challenges of filtration for the bioprocessing industry, where upstream cell culture clarification or downstream impurity removal is required, 3M™ Encapsulated Systems provide ergonomic, easy-to-use solutions. Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with ZB Series Media are available in three sizes to meet varying volumes and applications and have been designed for minimal hold-up volume. They also incorporate 3 feet and rubber shoes for a firm, level posture on many surfaces and can also be stacked for convenience. Applications Parenterals, Dialysates Pharmaceuticals Antibiotics Growth Media Blood Fractionation Bioprocess Fluids, especially cell harvest polishing Cosmetic Applications We utilize the lenticular filter design and vertical flow path that has proven eff

Suggested Applications

• Use for pharmaceuticals, antibiotics, growth media, blood Fractionation, bioprocess fluids, especially cell harvest polishing