Zeta Plus™ Encapsulated System Filter Capsule, EXT, with SP Series Media

• High contaminant holding capacity due to two layers of complementary porosities provides economical filtration and reliable particle reduction
• FDA Drug Master File and USP Class VI Biological Reactivity Tests eases validation and regulatory submissions
• Self-contained, single-use capsules are available in three convenient sizes for scale-up and benchtop studies
• Low hold-up volume for minimal fluid loss
• Novel shape to maintain the same lenticular flow path as larger capsules and cartridges
• Novel shape to maintain the same lenticular flow path as larger capsules and cartridges

We developed the Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with SP Series Media to provide economical small scale clarification of pharmaceutical, biological, bioprocess, and cosmetic fluids. Our depth filtration media is composed of inorganic filter aid, cellulose and a positively charged resin system that that pulls negatively charged contaminants from the fluid.

Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with SP Series Media are a family of advanced dual layer depth filters that are designed to provide superior clarification of bioprocess, biological, and pharmaceutical fluids. They are optimized for clarification of mammalian cell harvest fluids and for protection of downstream sterilizing grade membrane filters. Their slight positive charge can provide more reduction of negatively charged contaminants compared to a mechanical filtration mechanism alone. Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with SP Series Media products are manufactured to stringent quality controls to provide reproducible product performance from filter to filter, lot to lot. When used as a pre-filter, the high contaminant holding capacity of Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with SP Series Media can prolong the life of the final stage filter. Pharmaceutical Grade Media Zeta Plus™ Encapsulated System Scale-Up Filter Capsules, EXT, with SP Series Media are manufactured to controls described in our Drug Master File on record with the FDA. Certificates of Quality are included with every filter. These filters meet the requirements of USP Class VI Biological Reactivity Tests and meet the strict requirements specified in the Drug Master File, including product control and traceability. Encapsulating High Performance When faced with the challenges of filtration for the bioprocessing industry, where upstream cell culture clarification or downstream impurity removal is required, 3M Encapsulated Systems provide an ergonomic, easy-to-use solution. The Scale-Up Capsules are available in three sizes to meet varying volumes and applications and the capsules have been designed for minimal hold-up volume. They also incorporate 3 feet and rubber shoes for a level posture on many surfaces and can be stacked for convenience. Applications Parenterals, Dialysates Pharmaceuticals Ant

Suggested Applications

• Use for pharmaceuticals, antibiotics, growth media, blood fractionation, bioprocess fluids, especially cell harvests applications