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3M™ Emphaze™ AEX Series Hybrid Purifier

  • Reduces turbidity, HCP, DNA and bioburden
  • Excellent throughput and mAb recovery
  • Enhanced capture column performance and protection
  • Substantial turbidity, DNA, HCP and bioburden reduction
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Overall Diameter (Metric)
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Overall Length (Metric)
Overall_Length_Metric
Overall Width (Metric)
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Overall Height (Metric)
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Micron Rating
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 Overall Diameter (Metric), Overall Length (Metric), Overall Width (Metric), Overall Height (Metric)  Micron Rating
All Models
  • Overall Diameter (Metric)
    Overall Length (Metric)
    Overall Width (Metric)
    Micron Rating
    Filter Type
    Overall Height (Metric)
  • 3M™ Emphaze™ AEX Series Hybrid Purifier BV8R, EMP303AEX020R, Sanitary, 2/Case
    Overall Diameter (Metric)
    7.7 cm
    Overall Length (Metric)
    8.8 cm
    Overall Width (Metric)
    7.7 cm
    Micron Rating
    0.2 μm
    Filter Type
    Filter Capsule
    Overall Height (Metric)
    8.8 cm
  • 3M™ Emphaze™ AEX Series Hybrid Purifier, BV8R, EMP301AEX020R, Luer, 2/Case
    Overall Diameter (Metric)
    7.7 cm
    Overall Length (Metric)
    4.5 cm
    Overall Width (Metric)
    7.7 cm
    Micron Rating
    0.2 μm
    Filter Type
    Filter Capsule
    Overall Height (Metric)
    4.5 cm
  • 3M™ Emphaze™ AEX Series Hybrid Purifier BV120R, EMP513AEX020R, 1/Case
    Overall Diameter (Metric)
    21.6 cm
    Overall Length (Metric)
    21.6 cm
    Overall Width (Metric)
    10.3 cm
    Micron Rating
    0.2 μm
    Filter Type
    Filter Capsule
    Overall Height (Metric)
    10.3 cm
  • 3M™ Emphaze™ AEX Series Hybrid Purifier BV0.3R, EMP101AEX020R, 4/Case
    Overall Diameter (Metric)
    2.2 cm
    Overall Length (Metric)
    29.6 cm
    Overall Width (Metric)
    21.5 cm
    Filter Type
    Filter Capsule
    Overall Height (Metric)
    3 cm
  • 3M™ Emphaze™ AEX Series Hybrid Purifier BV1R, EMP201AEX020R, 4/Case
    Overall Diameter (Metric)
    3.7 cm
    Overall Length (Metric)
    48.4 cm
    Overall Width (Metric)
    37 cm
    Filter Type
    Filter Capsule
    Overall Height (Metric)
    4.8 cm
  • 3M™ Emphaze™ AEX Series Hybrid Purifier BV360R, EMP533AEX020R, 1/Case
    Overall Diameter (Metric)
    21.6 cm
    Overall Length (Metric)
    15.2 cm
    Overall Width (Metric)
    21.6 cm
    Micron Rating
    0.2 μm
    Filter Type
    Filter Capsule
    Overall Height (Metric)
    15.2 cm
  • 3M™ Emphaze™ AEX Series Hybrid Purifier BV5600R, EMP770AEX020R, 1/Case
    Overall Diameter (Metric)
    45.2 cm
    Overall Length (Metric)
    20.3 cm
    Overall Width (Metric)
    45.2 cm
    Micron Rating
    0.2 μm
    Filter Type
    Filter Capsule
    Overall Height (Metric)
    20.3 cm
  • 3M™ Emphaze™ AEX Series Hybrid Purifier, BV60R, EMP503AEX020R, 1/Case
    Overall Diameter (Metric)
    21.6 cm
    Overall Length (Metric)
    10.1 cm
    Overall Width (Metric)
    24.1 cm
    Filter Type
    Filter Capsule
    Overall Height (Metric)
    10.3 cm
  • 3M™ Emphaze™ AEX Series Hybrid Purifier BV800R, EMP710AEX020R, 1/Case
    Overall Diameter (Metric)
    45.2 cm
    Overall Length (Metric)
    5.7 cm
    Overall Width (Metric)
    45.2 cm
    Micron Rating
    0.2 μm
    Filter Type
    Filter Capsule
    Overall Height (Metric)
    5.7 cm
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Specifications
Applications
Adsorptive Depth Filtration, Bioburden Reduction, Cell Culture Clarification, Chromatography and Column Protection, DNA Removal
Brand
Emphaze™
Dimensions (metric)
10.3 cm x 21.6 cm, 15.2 cm x 21.6 cm, 20.3 cm x 45.2 cm, 4.5 cm x 7.7 cm, 5.7 cm x 45.2 cm, 8.8 cm x 7.7 cm
Filter Material
All-Synthetic Hybrid
Filter Type
Filter Capsule
Flow Rate (metric)
0.3 Millilitre per Minute, 1 Millilitre per Minute, 100 Millilitre per Minute, 300 Millilitre per Minute, 4700 Millilitre per Minute, 50 Millilitre per Minute, 680 Millilitre per Minute, 8 Millilitre per Minute
Industries
Life Sciences
Maximum Operating Temperature (Celsius)
40 Degree Celsius
Micron Rating
0.2 μm
Product Series
AEX
Series
Emphaze™ AEX, Emphaze™ AEX Series
Storage Temperature
68
Units per Case
1, 2, 4
Product Details
  • Reduces turbidity, HCP, DNA and bioburden
  • Excellent throughput and mAb recovery
  • Enhanced capture column performance and protection
  • Substantial turbidity, DNA, HCP and bioburden reduction
  • Reduced surface area requirement of the downstream sterilizing grade membrane
  • May offer differentiated protection of the protein A column for enhanced contaminant clearance performance
  • All product components comply with United States Pharmacopeia (USP) <88> Class VI 70°C Biological Reactivity Tests, in vivo
  • Autoclavable

3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer. The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 X range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule. Capsules There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules: - The Laboratory capsule (BV8) has an 8ml bed volume - The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 mls and 360 mls (BV 120 and BV 360 respectively) - The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.

Suggested Applications

  • Use for the clarification of mammalian cell cultures and to optimise downstream processes for monoclonal antibodies (mAbs)
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